Now a detective-for-hire like her infamous brother, Enola Holmes takes on her first official case to find a missing girl, as the sparks of a dangerous conspiracy ignite a mystery that requires the help of friends — and Sherlock himself — to unravel. Enola Holmes takes on her first case as a detective, but to unravel the mystery of a missing girl, she'll need some help from friends -- and brother Sherlock. After starting her own detective agency, Enola Holmes is search for clients when she stumbles upon a new mystery.